solute carrier family 6 member 4
mammalian protein found in Homo sapiens
osa objektist
Sodium:neurotransmitter symporter superfamily[13]
Sodium:neurotransmitter symporter, serotonin, N-terminal domain, protein family[15]
found in taxon
Homo sapiens[9]
encoded by
SLC6A4[9]
molecular function
cell component
biological process
physically interacts with
facilitates flow of
täpne vaste
koosseisu osa
Sodium:neurotransmitter symporter, serotonin, N-terminal[13]
Commonsi kategooria
Serotonin transporters
Viited
- ↑ NCBI Gene, 30. mai 2020, 6532
- ↑ Transporter Classification database, 13. märts 2020
- ↑ Transporter Classification database, 29. aprill 2020
- ↑ Ensembl Release 99, ENSP00000261707
- ↑ Ensembl Release 99, ENSP00000385822
- ↑ Ensembl Release 99, ENSP00000378298
- ↑ Ensembl Release 99, ENSP00000463172
- ↑ Ensembl Release 99, ENSP00000498537
- ↑ 9,0 9,1 9,2 9,3 UniProt, 13. november 2019, P31645
- ↑ Freebase Data Dumps, 28. oktoober 2013
- ↑ 11,0 11,1 11,2 11,3 11,4 11,5 P31645, 9. august 2016, UniProt, inglise keel
- ↑ OpenAlex, 26. jaanuar 2022, https://docs.openalex.org/download-snapshot/snapshot-data-format
- ↑ 13,0 13,1 13,2 InterPro Release 71.0, http://www.ebi.ac.uk/interpro/protein/P31645
- ↑ 2.A.22.1.1, 2. oktoober 2019, hierarchical database ID heuristic
- ↑ inferred from protein domain or family
- ↑ 16,00 16,01 16,02 16,03 16,04 16,05 16,06 16,07 16,08 16,09 16,10 16,11 16,12 16,13 16,14 16,15 16,16 16,17 16,18 16,19 16,20 16,21 16,22 16,23 16,24 16,25 16,26 16,27 16,28 16,29 16,30 16,31 16,32 16,33 16,34 16,35 16,36 16,37 16,38 16,39 16,40 IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, 9. mai 2019, Ensembl genome database project, GOA
- ↑ 17,0 17,1 17,2 17,3 17,4 17,5 17,6 17,7 17,8 IEA, 9. mai 2019, P31645, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, UniProt
- ↑ 18,0 18,1 18,2 18,3 18,4 IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, 9. mai 2019, InterPro, GOA
- ↑ 19,0 19,1 19,2 19,3 ISS, 9. mai 2019, P31645, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, UniProt
- ↑ 20,0 20,1 IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, 9. mai 2019, Mouse Genome Informatics, IRIP, a new ischemia/reperfusion-inducible protein that participates in the regulation of transporter activity, GOA
- ↑ IPI, 9. mai 2019, P31645, Modulation of the trafficking of the human serotonin transporter by human alpha-synuclein, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, UniProt
- ↑ IPI, 9. mai 2019, P31645, Subcellular redistribution of the serotonin transporter by secretory carrier membrane protein 2, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, UniProt
- ↑ IPI, 9. mai 2019, P31645, Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, UniProt
- ↑ IPI, 9. mai 2019, P31645, The multiple LIM domain-containing adaptor protein Hic-5 synaptically colocalizes and interacts with the dopamine transporter, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, UniProt
- ↑ 25,0 25,1 TAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P31645&geneProductId=UniProtKB:P31645, 16. juuli 2018, Reactome, GOA
- ↑ IMP, 16. juuli 2018, P31645, Retracted: The Cellular Distribution of Serotonin Transporter Is Impeded on Serotonin-Altered Vimentin Network, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P31645&geneProductId=UniProtKB:P31645, UniProt
- ↑ 27,0 27,1 IEA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P31645&geneProductId=UniProtKB:P31645, 16. juuli 2018, InterPro, GOA
- ↑ 28,0 28,1 28,2 IEA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P31645&geneProductId=UniProtKB:P31645, 16. juuli 2018, Ensembl genome database project, GOA
- ↑ 29,0 29,1 IDA, 16. juuli 2018, P31645, Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P31645&geneProductId=UniProtKB:P31645, UniProt
- ↑ 30,0 30,1 30,2 IBA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P31645&geneProductId=UniProtKB:P31645, 16. juuli 2018, GO Central, GOA
- ↑ TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, 1. jaanuar 2018, Reactome, GOA
- ↑ IMP, 1. jaanuar 2018, P31645, Retracted: The Cellular Distribution of Serotonin Transporter Is Impeded on Serotonin-Altered Vimentin Network, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, UniProt
- ↑ 33,0 33,1 IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, 1. jaanuar 2018, InterPro, GOA
- ↑ 34,0 34,1 IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, 1. jaanuar 2018, Ensembl genome database project, GOA
- ↑ IDA, 1. jaanuar 2018, P31645, Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, UniProt
- ↑ IBA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, 1. jaanuar 2018, GO Central, Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium, GOA
- ↑ 37,0 37,1 37,2 37,3 37,4 IBA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, 9. mai 2019, GO Central, Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium, GOA
- ↑ 38,0 38,1 38,2 TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, 9. mai 2019, Reactome, GOA
- ↑ 39,0 39,1 IDA, 9. mai 2019, P31645, Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, UniProt
- ↑ 40,0 40,1 IDA, 1. jaanuar 2018, P31645, Retracted: The Cellular Distribution of Serotonin Transporter Is Impeded on Serotonin-Altered Vimentin Network, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, UniProt
- ↑ IC, 16. juuli 2018, P31645, Retracted: The Cellular Distribution of Serotonin Transporter Is Impeded on Serotonin-Altered Vimentin Network, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P31645&geneProductId=UniProtKB:P31645, UniProt
- ↑ 42,0 42,1 42,2 IDA, 9. mai 2019, P31645, Subcellular redistribution of the serotonin transporter by secretory carrier membrane protein 2, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, UniProt
- ↑ 43,0 43,1 43,2 IDA, 9. mai 2019, P31645, Serotonin transamidates Rab4 and facilitates its binding to the C terminus of serotonin transporter, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, UniProt
- ↑ 44,0 44,1 44,2 IDA, 9. mai 2019, P31645, Plasma serotonin levels and the platelet serotonin transporter, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, UniProt
- ↑ IEA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P31645&geneProductId=UniProtKB:P31645, 1. jaanuar 2018, Gene Ontology Consortium, GOA
- ↑ IEA, 16. juuli 2018, P31645, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P31645&geneProductId=UniProtKB:P31645, UniProt
- ↑ 47,0 47,1 IDA, 16. juuli 2018, P31645, Retracted: The Cellular Distribution of Serotonin Transporter Is Impeded on Serotonin-Altered Vimentin Network, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P31645&geneProductId=UniProtKB:P31645, UniProt
- ↑ 48,0 48,1 IDA, 16. juuli 2018, P31645, Plasma serotonin levels and the platelet serotonin transporter, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P31645&geneProductId=UniProtKB:P31645, UniProt
- ↑ 49,0 49,1 IDA, 16. juuli 2018, P31645, Serotonin transamidates Rab4 and facilitates its binding to the C terminus of serotonin transporter, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P31645&geneProductId=UniProtKB:P31645, UniProt
- ↑ 50,0 50,1 IDA, 16. juuli 2018, P31645, Subcellular redistribution of the serotonin transporter by secretory carrier membrane protein 2, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P31645&geneProductId=UniProtKB:P31645, UniProt
- ↑ IC, 1. jaanuar 2018, P31645, Retracted: The Cellular Distribution of Serotonin Transporter Is Impeded on Serotonin-Altered Vimentin Network, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, UniProt
- ↑ IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, 9. mai 2019, Gene Ontology Consortium, GOA
- ↑ 53,0 53,1 53,2 ISS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, 9. mai 2019, British Heart Foundation, GOA
- ↑ IMP, http://www.ebi.ac.uk/QuickGO/annotations?protein=P31645&geneProductId=UniProtKB:P31645, 16. juuli 2018, Community Assessment of Community Annotation with Ontologies, Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization, GOA
- ↑ IDA, 9. mai 2019, P31645, Differential expression of intestinal membrane transporters in cholera patients, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, UniProt
- ↑ IMP, 9. mai 2019, P31645, Major depression, 5HTTLPR genotype, suicide and antidepressant influences on thalamic volume, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, UniProt
- ↑ IMP, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31645, 9. mai 2019, Community Assessment of Community Annotation with Ontologies, Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization, GOA
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 200, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 201, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7118, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7547, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 4621, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 2398, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7901, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 2399, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7158, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 202, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7177, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 203, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7189, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 357, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7435, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7551, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7247, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 2404, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 4790, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7266, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7285, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 4798, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 2586, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7317, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7321, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7427, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7351, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 59, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 103, inglise keel
- ↑ Identifiers.org