5-hydroxytryptamine receptor 1A
mammalian protein found in Homo sapiens
found in taxon
Homo sapiens[8]
encoded by
HTR1A[8]
molecular function
cell component
biological process
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger[20]
määramismeetod: IBA
physically interacts with
koosseisu osa
GPCR, rhodopsin-like, 7TM[9]
Commonsi kategooria
5-HT1A serotonin receptor
teema peakategooria
Category:5-HT1A serotonin receptor
Viited
- ↑ NCBI Gene, 30. mai 2020, 3350
- ↑ Transporter Classification database, 13. märts 2020
- ↑ Transporter Classification database, 29. aprill 2020
- ↑ https://www.wikidata.org/w/index.php?title=Wikidata:Property_proposal/Guide_to_Pharmacology_Target_ID&oldid=709819452
- ↑ OpenAlex, 26. jaanuar 2022, https://docs.openalex.org/download-snapshot/snapshot-data-format
- ↑ Ensembl Release 99, ENSP00000316244
- ↑ Ensembl Release 99, ENSP00000423433
- ↑ 8,0 8,1 8,2 8,3 UniProt, 13. november 2019, P08908
- ↑ 9,0 9,1 InterPro Release 71.0, http://www.ebi.ac.uk/interpro/protein/P08908
- ↑ inferred from protein domain or family
- ↑ IEA, 16. juuli 2018, P08908, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908, UniProt
- ↑ 12,0 12,1 12,2 IEA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908, 16. juuli 2018, InterPro, GOA
- ↑ IEA, 1. jaanuar 2018, P08908, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908, UniProt
- ↑ TAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908, 16. juuli 2018, Proteome Inc., Increase in serotonin-1A autoreceptors in the midbrain of suicide victims with major depression-postmortem evidence for decreased serotonin activity, GOA
- ↑ IMP, 16. juuli 2018, P08908, Role of glycosphingolipids in the function of human serotonin₁A receptors, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908, UniProt
- ↑ IEA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908, 16. juuli 2018, Ensembl genome database project, GOA
- ↑ 17,0 17,1 IDA, 16. juuli 2018, P08908, Expression of 5HT1a receptors on activated human T cells. Regulation of cyclic AMP levels and T cell proliferation by 5-hydroxytryptamine, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908, UniProt
- ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908, 8. aprill 2019, Parkinsons Disease Gene Ontology Initiative, Dynamic modulation of FGFR1-5-HT1A heteroreceptor complexes. Agonist treatment enhances participation of FGFR1 and 5-HT1A homodimers and recruitment of β-arrestin2, GOA
- ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908, 8. aprill 2019, IntAct protein interaction database, Fibroblast growth factor receptor 1- 5-hydroxytryptamine 1A heteroreceptor complexes and their enhancement of hippocampal plasticity, GOA
- ↑ 20,0 20,1 20,2 20,3 20,4 20,5 20,6 20,7 20,8 IBA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908, 8. aprill 2019, GO Central, Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium, GOA
- ↑ IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908, 8. aprill 2019, Parkinsons Disease Gene Ontology Initiative, Dynamic modulation of FGFR1-5-HT1A heteroreceptor complexes. Agonist treatment enhances participation of FGFR1 and 5-HT1A homodimers and recruitment of β-arrestin2, GOA
- ↑ 22,0 22,1 22,2 22,3 22,4 22,5 22,6 IEA, 8. aprill 2019, P08908, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908, UniProt
- ↑ 23,0 23,1 23,2 23,3 23,4 23,5 23,6 23,7 23,8 IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908, 8. aprill 2019, InterPro, GOA
- ↑ TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908, 8. aprill 2019, Proteome Inc., Increase in serotonin-1A autoreceptors in the midbrain of suicide victims with major depression-postmortem evidence for decreased serotonin activity, GOA
- ↑ 25,0 25,1 IMP, 8. aprill 2019, P08908, Role of glycosphingolipids in the function of human serotonin₁A receptors, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908, UniProt
- ↑ 26,0 26,1 26,2 26,3 26,4 26,5 26,6 IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908, 8. aprill 2019, Ensembl genome database project, GOA
- ↑ 27,0 27,1 IDA, 8. aprill 2019, P08908, Expression of 5HT1a receptors on activated human T cells. Regulation of cyclic AMP levels and T cell proliferation by 5-hydroxytryptamine, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908, UniProt
- ↑ 28,0 28,1 TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908, 8. aprill 2019, Reactome, GOA
- ↑ TAS, http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908, 16. juuli 2018, Proteome Inc., The genomic clone G-21 which resembles a beta-adrenergic receptor sequence encodes the 5-HT1A receptor, GOA
- ↑ IDA, 16. juuli 2018, P08908, Role of glycosphingolipids in the function of human serotonin₁A receptors, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908, UniProt
- ↑ TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908, 8. aprill 2019, Proteome Inc., The genomic clone G-21 which resembles a beta-adrenergic receptor sequence encodes the 5-HT1A receptor, GOA
- ↑ IDA, 8. aprill 2019, P08908, Role of glycosphingolipids in the function of human serotonin₁A receptors, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908, UniProt
- ↑ 33,0 33,1 TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908, 8. aprill 2019, Proteome Inc., Activation of 5-HT1A receptors expressed in NIH-3T3 cells induces focus formation and potentiates EGF effect on DNA synthesis, GOA
- ↑ 34,0 34,1 34,2 34,3 34,4 34,5 ISS, 8. aprill 2019, P08908, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908, UniProt
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 8182, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7191, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 8434, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 8436, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 8435, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 3, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 4, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 5, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 31, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 34, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 8, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 37, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 38, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 11, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 39, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 40, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 12, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 1, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 43, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 17, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 19, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 20, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 44, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 45, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 3924, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 46, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 47, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 50, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 2, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 51, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 23, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 24, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 25, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 53, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 54, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 55, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 30, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 57, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 58, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 60, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 33, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 9, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 10, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 35, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 36, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 41, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 14, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 42, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 48, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 49, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 52, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 26, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 32, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 28, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 56, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7427, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7351, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 59, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 62, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 83, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 84, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 85, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 86, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 87, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 68, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 88, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 7227, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 89, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 73, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 90, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 91, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 92, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 93, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 94, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 95, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 96, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 97, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 72, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 98, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 99, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 100, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 101, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 79, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 80, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 102, inglise keel
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17. august 2016, 103, inglise keel
- ↑ Open Targets Platform, 14. august 2023, https://platform.opentargets.org/drug/CHEMBL1512580
- ↑ Open Targets Platform, 14. august 2023, https://platform.opentargets.org/drug/CHEMBL37744
- ↑ Open Targets Platform, 14. august 2023, https://platform.opentargets.org/drug/CHEMBL2219425
- ↑ Open Targets Platform, 14. august 2023, https://platform.opentargets.org/drug/CHEMBL284092
- ↑ Open Targets Platform, 14. august 2023, https://platform.opentargets.org/drug/CHEMBL1200399